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These systemic effects are uncommon at standard therapeutic doses

[DOI] [PubMed] [Google Scholar] 17.Esposito D., Chatterjee D.K

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On the other hand, the lack of a significant anxiolytic effect with GABA treatment raises questions about its bioavailability or receptor interactions in the specific context of the EPM test, possibly due to differences in the route of administration, dosage, or the animal models specific pathology

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