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The tumor microenvironment has low levels of glucose

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However, no significant differences were observed between WT and EAAC1 / mice in either young (WT, 1.52 0.31

Angiogenic effects Mutations: Loss of function of thymidine phosphorylase MNGIE patients Most patients: Absent, or nearly complete loss of, TP function Milder patients may have residual activity Measured in leukocytes Carriers: ~ 35% of normal activity

Odds ratios higher than 1 reflect a higher discontinuation rate due to adverse events in the substance class arms, whereas odds ratios lower than 1 reflect a higher discontinuation rate due to adverse events in the placebo arms

1) Patients with hypersensitivity reaction to thioctic acid (a-lipoic acid) and components of this drug 2) Children and adolescents (less clinical experience) 3