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Indeed, although many studies have clearly shown that several interventions including pharmacological therapy and lifestyle modifications improve endothelial function under the condition of relatively mild vascular endothelial dysfunction [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35], we have shown that advanced endothelial dysfunction is not reversible even by appropriate pharmacological therapy [94]

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Steroids are also commonly prescribed (ACS 2013)

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Pancreatology 2003;3:13943

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Schilling A, Corey R, Leonard M, Eghtesad B

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Durak , zbek H, Karaayvaz M, ztrk HS (2002) Cisplatin induces acute renal failure by impairing antioxidant system in Guinea pigs: effects of antioxidant supplementation on the cisplatin nephrotoxicity

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