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Slovak J Food Sci

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinsons Disease

This is especially damaging in neurodegenerative diseases as the chronic inflammatory state directly contributes to neuronal cell death and synaptic dysfunction

Recently, phytomedicine has shown prophylactic and therapeutic potential in PD due to its antioxidant [12,13,14], anti-inflammatory [15] and antiapoptotic effects [16, 17]

After the addition of the STAT3 inhibitor BP-1-102, the expression levels of Nrf2 and GPX4 in cisplatin-resistant osteosarcoma cells were significantly reduced

Table 2 Classification of dopamine agonists