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& Yang, J

These drugs work by enhancing the effect of GABA at GABA-A receptors in the brain, producing calming, sedative, and muscle-relaxing effects

Most relevant peptides: Thymosin alpha-1 for expanding regulatory B cell subsets and reducing relapse frequency Thymosin beta-4/TB-500 for promoting remyelination through OPC differentiation BPC-157 for neuroprotective anti-inflammatory effects The Giacomini et al

These are mechanistically different agents at opposite ends of the regulatory ladder

However, long-term use of levodopa often leads to side effects, including fluctuations in motor movements characterized by on and off periods, where the effectiveness of levodopa reported to vary throughout the day

Not all of them do what they claim to, and many have concerning side effects