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Informed consent was obtained from all participants in the study and the study was approved by the Scientific Ethical Committee of Rennes Hospital in France (Avis n 22.185)

In addition, reactive metabolites-proteins adducts are thought to be a principal factor in natural drug-induced liver injury

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G6PD mutations lead to a range of enzyme deficiency phenotypes as classified by the World Health Organization, characterized by decreased enzyme stability and/or reduced G6PD enzyme activity