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RNA-sequencing data indicated hepatic EPHX1 level in MASLD patients was significantly higher than healthy control, and significantly correlated with transforming growth factor-1 ( TGFB1 ) and collagen type 1 alpha 1 ( COL1A1 )

Moreover, lactate-mediated H3K18 lactylation positively regulates the transcription of tumor necrosis factor superfamily member 9 (TNFSF9), further linking lactate metabolism with M2 polarization events [171]

Killed Saccharomyces cerevisiae protects against lethal challenge of Cryptococcus grubii

Although schizophrenia is associated with accelerated cognitive aging and an increased burden of vascular risk factors (4, 10), subtype-specific data on VaD progression in this population are currently lacking

Post hoc multiple comparisons were made using the Tukey-Kramer test

68, doi:10.1186/1750-1172-7-68