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HGSOC remains the most deadly gynecological cancer in the US and often faces difficulty in treatment success due to its late-stage diagnosis [4]

Current hypotheses for the spread of cell damage in neurodegenerative conditions, such as a prion-like spread of aggregated protein, are not able to explain these extra-CNS phenomena, whereas toxic metals can account for both CNS and associated non-CNS disorders

In some instances it seems likely that GSTs are induced by the general oxidative stress caused by these diverse treatments, but in other cases GST induction is specific to the particular stress [27]

US patent 20140200201 A1

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