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The stress may be due to: Overuse of the tendon Degeneration of the tendon Intense physical activity A sudden increase in activity Tight calf muscles Bone spurs or extra bone growth Types of Achilles Tendinitis Based on which part of the tendon is affected, Achilles tendinitis can be differentiated into: Insertional Achilles tendinitis: In this type, the lower portion of the tendon, where it attaches (inserts) to the heel bone is inflamed due to bone spurs

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Collectively, NOXs and the ETC generate roughly 85% of H 2 O 2 , with the remaining production deriving from oxidases in the endoplasmic reticulum (ER) and peroxisomes, as well as from cumulative environmental stressors such as UV or ionising radiation 8,40,42,43

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