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A: Yes, topical formulations containing 0.1-1% GHK-Cu and 1-5% NAD+ show significant improvements in skin hydration, elasticity, and wrinkle reduction

Some of these patients represent a late diagnosis of WD, and although medical therapy has been tried, the patient has not responded well to treatment

PMID: 20422495, PMCID: PMC3008346, DOI: 10.1055/s-0030-1253222

Zhao Y, Liu Y, Xu Y, Li K, Zhou L, Qiao H, et al

Figure 4 also shows that CoQ10 ( Figures 4C,D ) or creatine ( Figures 4E,F ) diet supplementation prevented MPT in the liver mitochondria of pravastatin treated LDLr -/- mice