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Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis

The effect of this synergistic treatment is ASS-dependent, and the activity of the enzymes mentioned above can be restored by transfection of ASS, eliminating the sensitivity of tumor cells to ADI-PEG20 combined with 5-FU treatment

This was then employed as a template for the generation of all mutant forms, which were obtained through overlap PCR with individual primers pairs (Supplementary Table 2)

Where do advanced glycation end products come from in the body