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The modeling of TM16-TM17 allows the identification of putative residues for the stimulated transport of GSH The above results led us to conclude that among the expressed chimeras, M8 is the most significantly affected both for inducing CS and for its GSH-dependent transport activity

Sakamoto I, Kishida S, Fukui A, Kishida M, Yamamoto H, Hino S, et al

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Regarding oxidative stress associated with mitochondrial complex I dysfunction and its role in BD, the importance of glutathione, an endogenous antioxidant, in preventing oxidative damage has been highlighted

J Cell Biochem 119:31113117 Zhai D, Ye Z, Jiang Y, Xu C, Ruan B, Yang Y, Lei X, Xiang A, Lu H, Zhu Z, Yan Z, Wei D, Li Q, Wang L, Lu Z (2017) MOTS-c peptide increases survival and decreases bacterial load in mice infected with MRSA

Over time, those deposits add up, creating a "cushion" that protects you during times of high stress or illness