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Trachootham et al., 2009)

Endocrinology 145 , 22532263 (2004)

Melatonin works as an antioxidant, attenuating neuroinflammation by altering the oxidative stress-induced gene expression profiles in SCI, such as peroxisome proliferator-activated receptors (PPAR-), toll-like receptor-4 (TLR4), nuclear factor kappa B (NF-B), and NRF2