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This condition requires lifelong intramuscular vitamin B12 therapy to prevent serious neurological complications

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The lack of B12 halts the methylation cycle, which leads to a buildup of toxic homocysteine

Understanding the role of pathways such as the PPP, which expurgate excessive amounts of ROS, might be crucial for finding an effective treatment against PD

doi:10.1007/s10354-016-0515-5 [23] Veijola LI, Oksanen AM, Sipponen PI, Rautelin HI