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TBOA blocked the increases in extracellular glutamate produced by the reverse dialysis of ammonia

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Troxerutin reverses fibrotic changes in the myocardium of high-fat high-fructose diet-fed mice

Over time, however, researchers came to understand that amylin has a distinct and important set of functions in regulating metabolism and food intake

Indeed, expression of senescent markers -gal, p21, p16, Bcl-2, Bcl-w and Bim was markedly reduced in Mdr2-/-Thy-1-/- and Mdr2-/- mice, while proliferation markers Ki67, Cyclin D, phospho-Akt were upregulated (vs Mdr2-/- or Mdr2-/-Thy-1-/- mice), suggesting that genetic deletion of Muc16 (which serves as a signal transduction receptor of Msln) and Msln prevents hepatocyte senescence in Mdr2-/- mice

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