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PMID 9480890

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Por ejemplo, Los polipptidos de FX modificados proporcionados en el presente documento, incluido el FX zimgeno modificado o FXa, tienen al menos dos sustituciones de aminocidos en un polipptido de FX sin modificar que es una sustitucin con S en una posicin que corresponde a la posicin 211 o una sustitucin con H en una posicin que corresponde a la posicin 219 con referencia a las posiciones de aminocidos que se muestran en la SEQ ID NO:134

G6PD-deficient variants that do not result in CNSHA are designated class II or class III, depending on the severity of the reduction in enzyme activity in red blood cells

successfully developed nanocurcumin and arginine-incorporated chitosan hydrogel, which demonstrated the ability to enhance the phosphorylation of eNOS in endothelial cells in vitro , along with antioxidant activity, effectively preventing hypoxia-induced endothelial injury (Mohandas and Rangasamy, 2021)

Transaminase upregulation and targeting of amino acid synthesis have the potential for cancer therapy