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MOTS-c appears to help muscle cells take up glucose independently of insulin, through a pathway that involves AMPK and GLUT4 transporters (the doors through which glucose enters muscle cells)

10.1007/s11033-020-05845-1 33 PalR.GulatiK.ChakrabortiA.BanerjeeB.RayA

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As shown in Figure 4B, treatment with 5 M DMF or 5M A alone did not induce significant cell death for up to 48 hours