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5 and 6) may be irrelevant to the mechanism of action for NMN treatment, and future work should aim to narrow the window of when NMN treatment offers its protection, to help identify when these molecular changes might be relevant to this phenotype

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For patients with changing renal function, monitor CrCl at least daily and adjust the dosage of ZERBAXA accordingly

However, theyre not considered sensitive, nor specific, and tend to only identify IDA not the early stages of iron depletion ( Identifying the earlier stages of depletion is beneficial, as doing so allows you to address the problem immediately be it through diet modifications or supplements rather than letting it progress to IDA before taking action