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DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated in 1977 that helps regulate deep, restorative sleep without the sedative hangover of traditional sleep medications

Peptides are valued in cosmetic formulations for helping improve the look of skin suppleness and contributing to a refreshed-looking complexion

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Moreover, the chemical nature of the C-terminal residue side chain determines ligand contact with RAMP and can influence activity at AMYRs and CTR 18,19