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The authors thank the following persons for their contributions to this work: Dolores Otero-Criado, Carlos Carvajales Fernndez, Rosa Zurdo-Baz and Raisa Gonzlez-Prez

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Symptoms of deficiencyfatigue, weakness, paraesthesia, cognitive impairment, and mood disturbancestypically improve significantly with appropriate replacement therapy

Companies did not properly warn people of dangers and made their products available in places where drugs and paraphernalia were sold

[2] Thakkar MM