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Liu H, Wilson IA

All infectious state where there is no specific indication

Second, when the amount of unbound drug in plasma increases, the rate of elimination will increase (if unbound clearance is unchanged), and after four half-lives the unbound concentration will return to its previous steady-state value

In a 23-week randomized clinical trial in humans, individuals taking AOD-9604 at 1 mg daily had an average of 2.8 kg weight reduction compared to a 0.8 kg weight reduction in those taking a placebo