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No significant effect on JNK MAP kinase was observed

Inflammation (2021) 44:223245

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Mateos et al., 1998)

GRADE-assessed systematic review and meta-analysis of clinical trials

In the case of troglitazone (an antidiabetic drug, voluntarily withdrawn from the market by the licence holder in 2000), it was reported that 1.95% of patients treated with troglitazone in clinical trials developed eleva-tions of aminotransferases that were greater than three times the upper limit of normal