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Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1/Mff regulation in head and neck squamous cell carcinoma

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For example, chitosan-modified taxifolin liposomes, via the specific binding between the cationic properties of chitosan and anionic sites on the surface of renal endothelial cells, not only enhance drug absorption efficiency and bioavailability but also accurately target renal injury sites, reduce total cholesterol and triglyceride levels in diabetic mice, alleviate damage to the glomerular filtration barrier caused by lipid metabolism disorders, and thereby protect renal function [201]

Numerous factors contribute to PF, including exposure to tobacco smoke, gastroesophageal reflux, viral and bacterial infections, silica dust inhalation, genetic variation, and immune disorders (Fig