labial melanotic freckle Mystery behind and oral macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome Definition of melanocytic macules associated

By preventing pathological increases in gut permeability, Larazotide reduces the passage of bacterial products (such as lipopolysaccharide/LPS) and food antigens across the gut barrier

Uchida K, Toyokuni S, Nishikawa K, Kawakishi S, Oda H, Hiai H et al

gnavus and Clostridium spp

Key Ingredients Water, Centella Asiatica Extract (12.3%), Glycerin, Cetyl Ethylhexanoate, Cetearyl Alcohol, Glyceryl Stearate, Glutathione (1,000ppm), Niacinamide (1,000ppm), Madecassic Acid, Asiaticoside, Asiatic Acid, Solanum Melongena (Eggplant) Fruit Extract, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hydrolyzed Collagen, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Squalane, Sodium Hyaluronate, Dipropylene Glycol, Butylene Glycol, Hydrogenated Lecithin, Cholesterol, Xanthan Gum, Potassium Hydroxide, Disodium EDTA, Caprylic/Capric Triglyceride, Cyclopentasiloxane, Cyclohexasiloxane, Saccharide Hydrolysate, Sorbitan Stearate, Dimethicone, PEG-100 Stearate, Stearic Acid, 1,2-Hexanediol, Chlorphenesin, Carbomer, Caprylyl Glycol

This creates Reactive Oxygen Species (ROS) which generate more oxidative stress

60:1107-1113 [PubMed: 22621222] 34