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Gastroenterology 152 , 313321 (2017)

Indeed, many of the traditional CVD risk factors, including oxidized low-density lipoprotein[313], hyperlipidemia (hypercholesterolemia or mixed dyslipidemia)[314] insulin resistance[309, 310, 312], diabetes[315], obesity[309, 311], elevated C-reactive protein[316], waist-to-hip ratio[309], reduced coronary flow reserve[279], smoking[317], sedentary life[318] and psychological distress[319], which act via effects on endothelial dysfunction, apoptosis and impaired endothelial-dependent vascular reactivity, have been associated with low serum IGF-I levels and reduced IGF-I and IGF-IR mRNA as well as protein expression in vascular smooth muscle cells (VSMC)[313]

It should be noted that my liver is in fairly good health I also see a Hepatologist at Shands and my liver was in a bit of remission ~ I was doing very well AND I wasnt experiencing any of the aforementioned symptoms until I received the Pfizer injection(s)

however, the prophylactic use of probiotics has been explored extensively

Other possible effects include water retention or changes in appetite and mood