Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant
Mitochondrial Ca 2+ handling is also disrupted, leading to the opening of the mitochondrial permeability transition pore (mPTP) and the release of cytochrome c, which triggers apoptosis
Cell-specific transcriptomics reveal pronounced age-dependent changes in glial gene expression, whereas the neuronal transcriptome shows only minor changes 178,179,180
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Calcium channel blockers (CCBs) and angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) are widely used anti-hypertensive drugs
