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The metabolomics data have been deposited to the EMBL-EBI MetaboLights database with the identifier MTBLS14139

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Dietary vitamin A modifies the gut microbiota and intestinal tissue transcriptome, impacting intestinal permeability and the release of inflammatory factors, thereby influencing A pathology

The primary driver of visceral obesity is an imbalance between intake and utilization of energy-dense metabolites (lipids and carbohydrates), the excess of which is converted to triacylglycerol (TAG) in the liver and in adipocytes [20,21]

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In addition to the described events at the cellular level, aging also promotes the dysfunction of the pineal gland, which is, as mentioned, an important source of melatonin, thus affecting several physiological processes mainly related to circadian rhythms