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such drugs inhibit mTOR kinase activity trough competing with ATP in order to bind to the mTOR kinase domain

Role of homocysteine in cognitive impairement and Alzheimers disease

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This recognition encouraged preclinical studies aiming to investigate both mechanistic aspects and intervention strategies to characterize and target this biological axis in conditions affecting muscle, brain, the immune system, and metabolic diseases

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For each sample, 1 g of total RNA was reverse-transcribed using a high-capacity cDNA reverse transcription kit (Applied Biosystems, Foster City, CA)