dihexa hgf c-met potentiator Activated HGF-c-Met Axis in Head and Neck Cancer Dihexa (also known as PNB-0408)
Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c MET pathway in cancer: from molecular characterization to clinical evidence Oncogene Growth factors and their peptide mimetics for treatment of traumatic brain injury ScienceDirect An overview of the c MET signaling pathway PMC Correlation between hypoxia and HGF c MET expression in the management of pancreatic cancer ScienceDirect Frontiers The Role of Hepatocyte Growth Factor (HGF) in Insulin Resistance and Diabetes
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