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Possible dual role of nitric oxide in oxidative stress injury: A study in perfused hepatocytes

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Indeed, in a recently completed Phase I trial of APR-246 in patients with haematological malignancies, it was noted that the addition of APR-246 to a patient receiving concurrent sorafenib resulted in complete remission of their acute myeloid leukaemia 35

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doi:10.1007/s11095-013-1025-4 Return to citation in text: [1] Mathew, A