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TB-500 (Thymosin 4) A synthetic peptide analog of thymosin 4, a naturally occurring 43-amino-acid peptide

Tissue samples were then placed in a homogenizer (Bulletblender Storm 24) for 5 min at 4 C at intensity level 6

Abbreviations EAU: Experimental autoimmune uveitis ROS: Reactive oxygen species IFN-: Interferon- IL-17: Interleukin-17 TNF-: Tumor necrosis factor- SOD: Superoxide dismutase TEM: Transmission electron microscopy DLS: Dynamic light scattering FTIR: Fourier transform infrared XPS: X-ray photoelectron spectroscopy DPPH: 1,1-diphenyl-2-picrylhydrazyl ABTS: 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) MB: Methylene blue ESR: Electron spin resonance PBMCs: Peripheral blood mononuclear cells CCK8: Cell counting kit-8 References Rosenbaum JT, Bodaghi B, Couto C, Zierhut M, Acharya N, Pavesio C, Tay-Kearney ML, Neri P, Douglas K, Pathai S, Song AP, Kron M, Foster CS

The 1 H-NMR and infrared spectroscopy were utilized to specify the structure of the synthesized final product

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Hydroxychloroquine does not prevent the future development of rheumatoid arthritis in a population with baseline high levels of antibodies to citrullinated protein antigens and absence of inflammatory arthritis: interim analysis of the StopRA trial