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Symptoms of pernicious anemia include: Excessive weakness, Pale skin, Diarrhea, Weight loss, Fever, Numbness or tingling sensation in the hands and feet, Imbalance, Confusion, Memory loss, and Mood swings

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The dysbiosis of gut microbiota caused by low-dose cadmium aggravate the injury of mice liver through increasing intestinal permeability

These data were also confirmed by the lower immunoscoring of IL-25, IL-33, TSLP, TUNEL, and caspase-3 compared to untreated mice with allergic airway inflammation

Hydrogel-based artificial mucosa restores local immune and microbial homeostasis for treating ulcerative colitis

In on illustrative, but non-limiting, embodiment, the CD8a hinge domain comprises or consists of the amino acid sequence Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr He Ala Ser Gin Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Glyl Ala Val Hhis Thr Arg Gly Leu Asp Phe Ala Cys Asp He Tyr (SEQ ID NO:76)