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The compound has been studied in trials lasting up to 68 weeks, which provides useful medium-term data but leaves questions about effects beyond 2 years of continuous use

The rats were randomly divided into 4 groups (each group of 20 rats): group A1 (normal control group under normoxia), group A2 (normal control group under normoxia, received low-dose l-carnitine at 50 mg/kg), group A3 (normal control group under normoxia, received high-dose l-carnitine at 100 mg/kg), group B (plateau model control group, received injecting normal saline), group C (low-dose l-carnitine intervention altitude model group, received 50 mg/kg l-carnitine) and group D (high-dose l-carnitine intervention altitude model group, received 100 mg/kg l-carnitine)

This is recognized as a significant obstacle to successful cancer immunotherapy.13 Reactive oxygen species (ROS) are chemically reactive derivatives of molecular oxygen produced in reduction-oxidation (redox) reactions during normal aerobic metabolism

10.3390/nu15030743 240 XuM.XuH.LingY.-W.LiuJ.-J.SongP.FangZ.-Q.et al (2025)