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In the ACTION trial, active surveillance involved the review, by the Data Safety Monitoring Committee, of the total number of patients screened for eligibility, who was eligible, asked for consent, and included plus response rates per study arm and per tumour type, the primary outcome measure and hospital admission and death data in both arms of the trial

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Naidoo J, Page DB, Li BT, Connell LC, Schindler K, Lacouture ME, Postow MA, Wolchok JD (2015) Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies