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While early, smaller trials showed promise by reducing infarct size (Piot et al., 2008), the larger CIRCUS trial subsequently failed to demonstrate improved clinical outcomes (Cung et al., 2015)

Across the 1980s and 1990s, GHK-Cu was studied extensively in wound healing applications, where it consistently demonstrated the ability to accelerate skin repair, stimulate collagen and glycosaminoglycan synthesis, and reduce inflammation at the site of injury

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Thus, there should be more focus on improving these herbs' bioavailability with the generation of minimum side effects