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Description

Disrupted energy metabolism Copper can directly or indirectly damage mitochondrial DNA (mtDNA), especially the D-loop region, which is critical for mtDNA replication and transcription (130)

Apart from the remethylation to Met, Hcy also drives the synthesis of cystathionine via cystathionine -synthase (CBS)

However, they share common symptoms such as: Fatigue

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J Biol Chem 276:70117016 Springael J, Penninckx MJ (2003) Nitrogen-source regulation of yeast -glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3