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Abstract As the main type of renal cell carcinoma (RCC), clear cell RCC (ccRCC) is often associated with the deletion or mutation of the von Hippel Lindau (VHL) gene, enhancement of glucose and lipid metabolism, and heterogeneity of the tumor microenvironment

In recent years, an increasing number of animal studies and preliminary clinical trials have investigated the impact of IF on fatty acid metabolism and the neuroimmune microenvironment, revealing its promising applications in neurodegenerative, autoimmune, and neurotraumatic diseases (3033)

"It is the GSH state that is needed to neutralise free radicals and protect the body from various toxins

Compared with several other GLP-1 receptor agonists, exenatide demonstrates stronger penetration of the bloodbrain barrier and a higher proportion entering the brain, and its clinical trials are more extensive [167]

Using higher concentrations (e.g

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