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In type II diabetes, the number of docked granules is about 1/3 lower than in normal cells, and the rate of glucose-stimulated exocytosis is only 20% of that in normal cells (Kwan and Gaisano, 2005)

This distinction is critical, as the field encompasses both specific enzymatic modifications and non-enzymatic chemical alterations that can occur under certain metabolic deficiencies or, more problematically, as technical artifacts during experimental procedures

Journal of strength and conditioning research , 22 (4), 11301135

Certain medicationsincluding proton pump inhibitors, metformin, and some anticonvulsantsmay affect the absorption or metabolism of specific nutrients

10.1016/j.pbb.2010.05.021 20 LiJ.CaoY.XuJ.LiJ.LvC.GaoQ.et al (2023)

doi: 10.1097/00000658-200107000-00014 32 WangHXPanWZhengLZhongXPTanLLiangZet al