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This can lead to higher production costs, potentially making the final product less accessible or affordable for widespread use ( 8.5.5.2 Scalability issues Translating laboratory-scale production of nanoformulations to industrial-scale manufacturing can be challenging

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Proteomic profiling of phosphatidylinositol 3-kinase (PI3K) altered metastatic colorectal cancer (mCRC) after protein kinase B (Akt) inhibition: Insulin like growth factor 1 receptor (IGF1R) mediates adaptive resistance

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These findings provide potential biomarkers for the early diagnosis and treatment of MS and EAE, and further suggest that targeting IDO1 or its metabolites may effectively regulate macrophage polarization and thereby improve disease prognosis

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