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PMID: 310 VasaikarSVStraubPWangJZhangB

This leads to transcriptional repression of lipogenic regulatorsincluding sterol regulatory element-binding protein 1c (SREBP1c), fatty acid synthase (FAS), and acetyl-CoA carboxylase (ACC)resulting in reduced hepatic steatosis, improved insulin sensitivity, and systemic metabolic restoration