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In summary, impaired prefrontal cortical function in elevated mood states may result in compromised regulation of limbic and paralimbic areas, manifesting as excessive emotional reactivity, irritability, impulsivity, difficulty conforming emotional responses to the social milieu, excessive indulgence of appetitive drives, and cognitive/attentional impairment

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Yue T-T, Zhang N, Li J-H, Lu X-Y, Wang X-C, Li X, et al