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Chinta SJ, Woods G, Rane A, Demaria M, Campisi J, et al

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For example, activation of transient receptor potential ankyrin 1 (TRPA1) induces Ca influx, promoting calmodulin-dependent protein kinase II (CaMKII) phosphorylation, and Nrf2 nuclear translocation, which upregulates GPX4 to inhibit ferroptosis in high-glucose-exposed endothelial cells, thereby improving cell migration, proliferation, and tube formation to enhance diabetic wound healing [87]

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pylori infection also induces systemically inflammatory immune responses in the host (Jackson et al., 2009)

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