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Although key nodal proteins (e.g., RIPK1, caspases, MLKL, GSDMs) and their regulatory interactions within these pathways have been identified [8, 9], the molecular mechanisms that integrate these signals, coordinate them spatiotemporally, and ultimately determine the cell death outcome remain a major knowledge gap

Jzwiak M et al., Pharmaceuticals, 2025

Inflammation and oxidative stress are closely interconnected, as the cellular damage imposed by increases in oxidative stress prompts immune inflammatory responses which contribute to the development and severity of neurodegeneration (Heneka et al., 2015)

The crRNA sequence must be followed by a short DNA sequence of 26 bp, known as the protospacer adjacent motif (PAM), which is important for Cas9 compatibility

Lipid abnormalities in streptozotocin-diabetes: amelioration by morus indica L

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