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Vitiligo: the association with metabolic syndrome and the role of simvastatin as an immunomodulator

By knocking down Cltc, the endocytosis of MPS into exocytosis in the spleen and liver can be significantly and specifically blocked, thus facilitating the efficient arrival of EVs to other tissues such as the heart

doi: 10.1016/j.cellsig.2010.06.004

Preclinical studies have confirmed that vitamin E supplementation significantly mitigates anxiety-like behaviors (103, 104) and reverses age-related immune disorders (105107)

see also van Exel et al., 2017

Some people may start to see results within a few weeks, while others may take longer