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Maternal betaine intake (rats and pigs) can programmatically alter liver metabolism, cell proliferation, and the developmental trajectory of offspringand even the F2 generationby affecting the DNA methylation pattern of the insulin-like growth factor (IGF) gene family (IGF-1/2) in the liver of the offspring and regulating the expression of glucocorticoid receptor signaling and lipolysis genes (adipose triglyceride lipase and hormone-sensitive lipase) (25, 140145)

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C.SaleemS.ZhenG.CaoW.ZhuangH.LeeJ.et al (2009)

External quality assessment of HLA-B*5701 reporting: an international multicentre survey

Characterization of variants of a human breast-cancer cell-line isolated from metastases in different organs of nude-mice