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Supplementary material The Supplementary Material for this article can be found online at: Footnotes 1.^ 2.^ 3.^ 4.^ 5.^ References 1 AebiH

The clinical trial can be accessed on (ClinicalTrials.gov Identifier: IRCT2017082434497N4)

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Moreover, supplementation with Se could enhance the expression of GPX4 in follicular helper T cells and increase the number of helper T cells to improve the antibody responsiveness of immunized mice after vaccination [30], indicating that the regulation of Se on GPX4 plays an essential role in normal mammalian embryos

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