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BM-MSC transplantation also enhanced the expression of mitochondrial superoxide dismutase 2 and Bcl-2, and inhibits the production of ROS

Another study providing pharmacological evidence of altered MTs regulation and its impact on Zn homeostasis in obesity was conducted by Mota Martins et al

Furthermore, immune-mediated pathways, including sclerostin inhibition of Wnt signaling and FGF-23 dysregulation, have emerged as critical regulators of mineral metabolism and potential therapeutic targets beyond conventional phosphate management (123, 124)

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Maintaining optimal levels of vitamin E may help prevent cognitive decline