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Molecular mechanisms of curcumin action: signal transduction

While Eli Lillys phase 2 trials reported side effects of mild-to-moderate gastrointestinal events, Poison Center data showed mounting cases of vomiting, fainting, rapid heart rate, and severe gastrointestinal distress

Thyroid dysfunctions, such as hypothyroidism, hyperthyroidism, Hashimotos thyroiditis, and Graves disease, affect millions worldwide

Factors such as poor diet, environmental toxins, stress, and certain medical conditions can further deplete glutathione levels

The 4-bromo-2-fluorobenzene moiety makes three hydrophobic contacts with residues I178 4.60 , L181 4.63 , and M213 5.39 in cavity II

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