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However, whether the neuroprotection occurs primarily within the dopamine neuron 38 , at extracellular 37 sites, or in glia remains unresolved

Clinical trials and meta-analyses have shown that long-term macrolide therapy significantly reduces exacerbation rates and sputum volume in bronchiectasis and COPD, with concomitant improvements in quality of life and attenuation of lung function decline [33, 95]

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Gowda NM, Wu X, Kumar S, Febbraio M, Gowda DC