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Polyphyllin I is a natural anti-tumor compound extracted from Paris polyphylla [151]

Deficiency in key autophagy molecules, such as Atg7 and Beclin-1, may contribute to DOR (Texada et al., 2019), as confirmed in animal studies

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Current medical management for all three conditions is based on attempts to find solutions from approved symptomatic medications, and while it is positive that women can be offered some options to deal with symptoms that severely impact their quality of life, these repurposed drugs and biologics offer only a band-aid solution, with none addressing the conditions underlying causes

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